SYNTAX: Integrated evidence synthesis for joint appraisal of tobacco and alcohol tax interventions for harm reduction in the UK
The SYNTAX project aimed to provide evidence and tools to inform the potential scale of effects of taxation across tobacco and alcohol as an intervention to improve public health and reduce health inequalities in the UK.
Introduction
Alcohol consumption and tobacco smoking are major modifiable risk factors for non-communicable diseases and people who both drink and smoke are at a further increased health risk.
Taxation is recognised worldwide as an effective way to reduce alcohol consumption and encourage smokers to quit, however there is a need to improve the evidence base upon which the joint effects of changes to tobacco and alcohol tax will be calculated. This means for example so that the relationships among alcohol and tobacco use and socioeconomic status can be considered.
Research tasks
This research developed new evidence on current and potential tobacco and alcohol pricing and tax policy in England. There were three key tasks:
- Understand the joint patterns of purchasing and use of the products across population subgroups.
- Use a consistent methodology to estimate the effects of industry influence on tax pass-through for off-trade alcohol, on-trade alcohol and tobacco.
- Produce more detailed evidence on how tobacco and alcohol consumption responds to price rises (the price elasticities of demand) and an understanding of the uncertainty in these estimates. For example, we need to better understand the extent to which consumers might quit smoking vs. switch to cheaper products.
Finally, the research plan recognised the need for impact assessment models capable of assessing the joint effects of tobacco and alcohol tax changes. This involves modelling the potential impact of combined tobacco and alcohol tax policy options on outcomes including changes in participation in drinking or smoking (any use vs abstinence), consumption levels, consumer expenditures, tax revenues to Government and net revenues to retailers, risk of harm related to 85 different clinical conditions, healthcare (NHS) costs, quality adjusted life years and mortality.
For information about the previous research that this project builds on see Partos et al. (2020) for tobacco and Meier et al. (2016) for alcohol.
Objectives
The objectives were designed to produce the evidence required for joint policy analysis of tobacco and alcohol tax policy changes.
Key project information

This project is funded by the National Institute for Health and Care Research (NIHR) under its Public Health Research programme (Project Ref 16/105/26). The views expressed are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care.
Dates
March 2018 – February 2021
Funding
£716,422.09
Chief investigator
Professor Alan Brennan
Institutions involved
University of Sheffield
University of Bath
Key contact
Details of the outputs from the SYNTAX project are available on the STAPM website.
Public involvement
The project team wanted to gain perspectives from people with lived experience on the options for tobacco and alcohol tax policy changes, and how any changes might affect people differently according to their alcohol and tobacco consumption and socio-demographic characteristics. They then used their understanding of the public perspectives to guide the process of generating and interpreting the research findings.
Three public panels were involved:
The Sheffield Addiction Recovery Research Panel
This group comprised former and current service users for drug and alcohol treatment and family and carers of people who have had experience of drug and alcohol misuse. Supported by the Clinical Research Office of Sheffield Teaching Hospitals NHS Foundation Trust.
The Tobacco and Nicotine Discussion Group in Nottingham
The Tobacco and Nicotine Discussion Group comprised current smokers or those trying to quit smoking who were experienced in discussing tobacco and new nicotine product use, tobacco control policy, approaches to smoking cessation and new developments in tobacco harm reduction. Funded as part of the UK Centre for Tobacco and Alcohol Studies (UKCTAS), and subsequently the SPECTRUM UK Prevention Research Partnership consortium.
The Alcohol and Food Discussion Group
This group comprised members of the public who were occasional or regular drinkers and experienced in discussing alcohol consumption, public health policy relating to alcohol and related research ideas and current projects. Also funded through UKCTAS and subsequently SPECTRUM.
Each panel was visited by SYNTAX researchers and members were guided through a structured discussion of alcohol and tobacco consumption behaviours, how consumption depends on product prices and available income, and their views on tax policy changes and its potential effects. These discussions were influenced by briefing information given to panel members including on the current rates of and revenues from tobacco and alcohol tax in the UK.
Outputs
Kai Le Chen R, Morris D, Angus C, Gilmore A, Hiscock R, Holmes J, Langley TE, Pryce R, Wilson LB, Brennan A, Gillespie D (2026) Reducing the exceptional affordability of hand-rolling tobacco using tax escalators: a health and economic impact modelling study for England Tobacco Control DOI: https://doi.org/10.1136/tc-2025-059670
Morris D, Angus C, Gillespie D, Stevely A, Pryce R, Wilson L, Henney M, Meier P, Holmes J, Brennan A (2024) Estimating the effect of transitioning to a strength-based alcohol tax system on alcohol consumption and health outcomes: a modelling study of tax reform in England The Lancet Public Health DOI: https://doi.org/10.1016/S2468-2667(24)00191-9
Morris D, Brennan A, Angus C, Wilson L, Pryce R, Gillespie D ([YEAR]) Tobacco and Alcohol Tax and Price Intervention Simulation Model (TAX-sim): full technical documentation. Documentation version number [x.x.x] University of Sheffield DOI: https://doi.org/10.17605/OSF.IO/KR23Z
Pryce R, Wilson LB, Gillespie D, Angus C, Morris D, Brennan A (2023) Estimation of integrated price elasticities for alcohol and tobacco in the United Kingdom using the living costs and food survey 2006–2017 Drug and Alcohol Review DOI: https://doi.org/10.1111/dar.13773
Hatchard J, Buykx P, Wilson L, Brennan A, Gillespie D (2023) Mapping alcohol and tobacco tax policy interventions to inform health and economic impact analyses: A United Kingdom based qualitative framework analysis International Journal of Drug Policy DOI: https://doi.org/10.1016/j.drugpo.2023.104247
Hatchard J, Buykx P, Brennan A, Gillespie D (2023) Options for modifying UK alcohol and tobacco tax: A rapid scoping review of the evidence over the period 1997–2018 [version 3; peer review: 2 approved] NIHR Open Research, 3:26. DOI: https://doi.org/10.3310/nihropenres.13379.3
Wilson LB, Angus C, Pryce R, Holmes J, Brennan A, Gillespie D (2021) Do dual purchasers behave differently? An analysis of purchasing data for households that buy both alcohol and tobacco in the United Kingdom Addiction DOI: https://doi.org/10.1111/add.15430
Wilson LB, Pryce R, Angus C, Hiscock R, Brennan A, Gillespie D (2021) The effect of alcohol tax changes on retail prices: how do on-trade alcohol retailers pass through tax changes to consumers? The European Journal of Health Economics DOI: https://doi.org/10.1007/s10198-020-01261-1
Wilson LB, Pryce R, Hiscock R, Angus C, Brennan A, Gillespie D (2020) Quantile regression of tobacco tax pass-through in the UK 2013–2019. How have manufacturers passed through tax changes for different tobacco products? Tobacco Control DOI: http://dx.doi.org/10.1136/tobaccocontrol-2020-055931
Hatchard J, Gillespie DOS, Buykx P (2019) 'Using framework analysis deductively: A case study from alcohol and tobacco tax policy and modelling research', in Clift B, Gore J Bekker S, Costas Batlle I, Chudzikowski K, Hatchard J (eds) Myths, Methods and Messiness: Insights for Qualitative Research Analysis: Edited Proceedings of the 5th Annual Qualitative Research Symposium Bath: University of Bath
Research team
Project Co-ordinators
- Prof Alan Brennan
- Dr Duncan Gillespie
Stakeholder interview team
- Dr Jenny Hatchard
- Dr Penny Buykx
Others involved in the project
- Ryan Kai Le Chen, Research Assistant, Sheffield Centre for Health and Related Research, University of Sheffield
- Anna Gilmore, Professor of Public Health, Department for Health, University of Bath
- Petra Meier, Professor of Public Health, Sheffield Centre for Health and Related Research, University of Sheffield
- John Holmes, Reader in Alcohol Policy, Sheffield Centre for Health and Related Research, University of Sheffield
- Colin Angus, Senior Research Fellow, Sheffield Centre for Health and Related Research, University of Sheffield
- Rosemary Hiscock, Research Associate, Department for Health, University of Bath
- Robert Pryce, Research Associate, Sheffield Centre for Health and Related Research, University of Sheffield
- Luke Wilson, Research Associate, Sheffield Centre for Health and Related Research, University of Sheffield
- Damon Morris, Research Associate, Sheffield Centre for Health and Related Research, University of Sheffield
- Grace Leeming, Research Assistant, Sheffield Centre for Health and Related Research, University of Sheffield
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